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CHLOROMETHANE, TOSYLPHENYLALANYL
Descriptors Found:
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DeCS
Descriptor
English
:
Tosylphenylalanyl Chloromethyl Ketone
Descriptor
Spanish
:
Clorometilcetona de Tosilfenilalanila
Descriptor
Portuguese
:
Tosilfenilalanil Clorometil Cetona
Synonyms
English
:
Chloromethane, Tosylphenylalanyl
Chloromethyl Ketone, Tosylphenylalanyl
Ketone, Tosylphenylalanyl Chloromethyl
Chlorophenyltosylamidobutanone
Tosylphenylalanyl Chloromethane
TPCK
Tree Number:
D02.455.426.559.389.832.710
D02.886.590.887.660
D12.125.065.930
Definition
English
:
An inhibitor of
Serine Endopeptidases
. Acts as alkylating agent and is known to interfere with the translation process.
Pharmacological Action:
Alkylating Agents
Protein Synthesis Inhibitors
Serine Proteinase Inhibitors
History Note
English
:
91(75); was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14500
Unique Identifier:
D014108
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS